The contribution of IL-1 signalling to long-term neurodegeneration, epilepsy and neurocognitive outcomes following traumatic injury to the paediatric brain

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1052505

Funding Status
Closed

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Funded Activity Summary

Epilepsy is a common, debilitating consequence of brain injury in children, however little is known about factors which trigger its development. This proposal investigates the contribution of the acute inflammatory response to long-term neuronal loss, functional outcomes and seizure activity after paediatric brain injury. Understanding how epilepsy and brain damage progresses after injury will aid the development of drugs to improve long-term outcomes in brain-injured children.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2017

Funding Scheme: Early Career Fellowships

Funding Amount: $394,670.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Central Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

brain development | cytokine signalling | electroencephalogram (EEG) | epilepsy | interleukins (IL) | nerve excitability | neuroanatomy | neurocognitive assessment | neuroinflammation | traumatic brain injury (TBI)

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