Modification of the microbiome and utilisation of microbial products as novel treatments for COPD

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1059239

Funding Status
Closed

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Funded Activity Summary

Smoking leads to lung inflammation that causes emphysema - a major health problem in Australia. Emphysema progressively declines even if smoking stops and there are no treatments. Recently changes in gut microbes have been linked to inducing or protecting against inflammation in the gut and lung. Thus we may be able to control inflammation by modifying these gut microbiomes. We may be able to ingest specific microbes or use specific antibiotics or other factors as new treatments for emphysema.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2018

Funding Scheme: Project Grants

Funding Amount: $1,226,338.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Respiratory Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

G protein-coupled receptors | antibiotic therapy | chronic obstructive pulmonary disease (COPD) | fatty acids | inflammation | microbial ecology | prevention | smoking-related diseases | steroid treatment | treatment

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