Innovative dosing approaches to maximise bacterial killing and prevent resistance in septic critically ill patients.

Funding Activity

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Funded Activity Summary

Patients in the intensive care unit (ICU) frequently die from infection. It remains unknown how important antibiotic dose optimisation is for these patients and whether it may enable more effective treatment. In this project, we propose to compare existing approaches to antibiotic dosing in ICU patients with innovative alternatives. We will determine which dosing approach results in better antibacterial efficacy and reduce the development of antibiotic resistance.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $830,364.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical Pharmacology and Therapeutics

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

antibiotic resistance | antibiotic therapy | intensive care medicine | pharmacokinetics | sepsis