Understanding the parameters of innate immune activation that govern protection during influenza virus and secondary bacterial infection: development of a TLR2-based antimicrobial agent.

Funding Activity

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Funded Activity Summary

Lower respiratory infections are the leading infectious cause of death worldwide. We have discovered a compound that reduces the impact and disease caused by viral and bacterial infections. This study will develop the prophylactic capabilities of this agent against transmission of influenza virus A and development of secondary bacterial disease. In addition, we will identify the mechanism of action for this compound, and its utility as a broad-spectrum intervention measure against viral and bacterial infections.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $462,420.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Immunology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

influenza virus | innate immunity | lung function | respiratory diseases | therapeutics | treatment strategies