Determining the biological significance of allelic sequence variation within the T cell receptor loci

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1067374

Funding Status
Closed

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Funded Activity Summary

T lymphocytes play a pivotal role in the immune system by recognising virus-infected tissue through the use of highly specific T cell receptors (TCRs). This project will investigate the importance of genetic variation in the TCR genes in influencing how we fight infections. Advances in these areas will assist in understanding susceptibility to some autoimmune diseases as well as aiding in the development of new "intelligent" vaccines and individualised therapeutics.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $627,549.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Immunology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Epstein-Barr virus (EBV) | T cell immunity | T cell receptor | cytotoxic T lymphocytes (CTL) | immunogenetics

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