Epigenetic regulation by lysine specific demethylases in breast cancer stem cells.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1068065

Funding Status
Closed

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Funded Activity Summary

The factors behind breast cancer recurrence are not fully understood but it is becoming increasingly evident that the spread of primary cancer can be initiated at a very early stage of cancer development by a small population of unique cancer cells, termed cancer stem cells (CSCs). Targeting of these CSCs has emerged as a priority area in cancer therapy. Our aim is to demonstrate that a novel class of epigenetic enzymes are key molecular targets of CSCs and propose a strategy to eradicate CSCs.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $590,860.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

breast cancer | chromatin structure | drug design | epigenetics | gene regulation | transcriptional regulation

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