Nanoparticle and virus assisted targeting of microRNA and DNA for the treatment of atherosclerosis, myocardial infarction and other inflammatory diseases

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1069492

Funding Status
Closed

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Funded Activity Summary

Inflammation is an underling cause or aggravating factor of many diseases, such as heart attack and atherosclerosis, but there is a lack of effective anti-inflammatory drugs that do not cause side effects. Using advanced biotechnology, we will use viruses and nanoparticles to selectively target gene therapeutics to areas of inflammation, resulting in high efficacy with low side effects. We will test these broadly usable therapeutics in mouse models of heart attack and atherosclerosis.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $663,583.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cardiology (incl. Cardiovascular Diseases)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

anti-inflammatory | atherosclerosis | microrna | myocardial infarction | nanotechnology | targeted gene delivery

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