Developing and testing pro-thrombotic conjugates for brain AVMs

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1085045

Funding Status
Closed

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Funded Activity Summary

Rupture of brain blood vessel abnormalities causes stroke in children and young adults. In this project, we will test new methods for occluding abnormal vessels. We use radiation first to induce changes in the vessels, and then target those changes to occlude the vessels. Successful treatment requires combining targeting and clot forming agents. In this project we will test combinations of targeting and clotting agents. The most effective combination will be progressed towards clinical trials.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $520,256.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

cerebrovascular disorders | radiation biology | stroke | thrombosis | vascular endothelium

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