DNA METHYLATION and DEMETHYLATION IMBALANCE in CANCER

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1088144

Funding Status
Closed

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Funded Activity Summary

This study will give us new insights into the role of MBD2 and TET proteins in establishing the epigenome and especially will have a major impact in our understanding of the key steps involved in both de novo DNA methylation and demethylation in cancer. Ultimately these new understandings may provide routes to use MBD2 and/or TET proteins as pharmacological targets in cancer treatment.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $635,443.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Epigenetics (incl. Genome Methylation and Epigenomics)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

DNA methylation | cancer cell biology | chromatin structure | epigenetics | gene expression

Related Links

ACN 633 798 857