New strategies to target multiple drug resistance in clinically relevant fungal infections.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1090444

Funding Status
Closed

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Funded Activity Summary

The emergence of multiple drug resistance (MDR) in the community and hospitals is considered a major threat to public health. Fungal bloodstream infections with opportunistic Candida species are of particular concern. Azoles are the most widely used class of antifungals in clinical use, but their efficacy is severely limited by the development of MDR. This project will employ a comprehensive, cross-disciplinary approach to develop novel small-molecule therapeutics for combatting fungal MDR.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2020

Funding Scheme: Early Career Fellowships

Funding Amount: $378,925.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Structural Biology (incl. Macromolecular Modelling)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

drug development | infectious diseases | protein characterisation | resistance spread | structural biology

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