Towards Targeting The Endosome In Neurodegenerative Disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1097185

Funding Status
Closed

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Funded Activity Summary

Mutations and dysregulation of the SNX27-retromer protein platform are strongly linked to Alzheimer’s disease (AD) and Parkinson’s disease (PD). This research program will determine how SNX27-retromer interacts with key molecules associated with AD and PD, the outcomes of which be significantly improved understanding of how mutations in these proteins cause disease, and a necessary molecular framework for future therapeutic targeting.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2019

Funding Scheme: Targeted Calls

Funding Amount: $601,959.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Structural Biology (incl. Macromolecular Modelling)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

X-ray crystallography | endosomes | membrane trafficking | molecular basis of disease | molecular neuroscience

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