Targeted direct reprogramming of adult cardiac fibroblasts to functional cardiomyocytes

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1107261

Funding Status
Closed

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Funded Activity Summary

Ischemic Heart Disease (IHD) is the leading cause of mortality in Australia, accounting for ~ 22,000 Australians each year. Regenerating a damaged heart remains a major challenge, requiring us to rethink the problem and develop new innovative and readily translatable strategies. This proposal will develop a targeted, cell-free approach to directly reprogram resident cardiac fibroblasts into functional cardiomyocytes post a heart attack, paving the way for a new therapy for IHD sufferers.

Funded Activity Details

Start Date: 01-01-2016

End Date: 01-01-2018

Funding Scheme: Project Grants

Funding Amount: $618,493.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gene and Molecular Therapy

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

acute myocardial infarction (AMI) | biomaterials | gene delivery | nanotechnology | regenerative medicine

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