Neurodegenerative disease pathology, mechanisms, models and treatments

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1140386

Funding Status
Closed

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Funded Activity Summary

Frontotemporal dementia (FTD) and motor neuron disease (MND) are fatal and incurable neurodegenerative diseases. Although dissimilar in symptoms, most cases of both FTD and MND are characterised at autopsy by abnormal accumulations of the TDP-43 protein in neurons. In this fellowship, I will characterise the biochemical changes caused by TDP-43 malfunction that occur in both FTD and MND and test potential new therapeutics in mice, to identify new ways to treat these devastating diseases.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2022

Funding Scheme: Career Development Fellowships

Funding Amount: $431,000.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Neurology and Neuromuscular Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

frontotemporal dementia | motor neuron disease (MND) | mouse models | neurodegeneration | pathology

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