Control of Alveolar Epithelial Cell Differentiation Before and After Birth

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/194436

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

In the lung, gas exchange takes place in small terminal airsacs called alveoli. The internal surface of the alveoli are lined with 2 types of specialist cells, the type-I and type-II cells, which are essential for the normal functioning of the lung. Although both cell types look completely different and have very different functions, they are derived from the same precursor cell. However, it is not known what determines whether these cells will become a type-I or a type-II cell. This application is directed towards understanding the mechanisms which determine the fate of these cells. This is critical information as the lung must have the correct proportions of both cell types to function properly as a gas exchange organ.

Funded Activity Details

Start Date: 01-01-2002

End Date: 01-01-2004

Funding Scheme: NHMRC Project Grants

Funding Amount: $376,980.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Public health nutrition

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

alveolar epithelial cells | cellular differentiation | corticosteroids | fetus | lung development | lung immaturity | respiratory insufficiency in the newborn | surfactant insufficency

Related Links