Targeting PD-1 expressing T-peripheral helper (Tph) cells and dysregulated checkpoint molecules: Improving outcomes in Rheumatoid Arthritis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/2004839

Funding Status
Status not available

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Funded Activity Summary

Rheumatoid arthritis is a chronic disease, causing pain, swelling and irreversible deformity of the joints. We propose to investigate the immune cell environment that drives this disease. In particular, we will focus on a new type of cell called Tph cells and related immune pathways. We will also study how they may be used as therapeutic targets or as markers to monitor disease activity. Our findings may translate into clinical practice and form a basis for new therapeutic strategies.

Funded Activity Details

Start Date: 01-01-2020

End Date: End date not available

Funding Scheme: Ideas Grants

Funding Amount: $597,168.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

drug targeting | rheumatoid arthritis | signalling pathways | t cells

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