Role of the tetraspanin CD151 in epithelial biology and cancer

Funding Activity

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Funded Activity Summary

A cell surface protein identified in this laboratory has been linked to cancer progression and metastasis. This project aims to examine the molecular basis of the action of the protein in regulating cell migration, and to establish model systems to provide definitive evidence as to its role in the development and progression of cancer. The models will also provide systems for future studies to evaluate the potential of antibodies and other inhibitors of the action of this protein as therapeutics in a range of human cancers.

Funded Activity Details

Start Date: 01-01-2005

End Date: 01-01-2007

Funding Scheme: NHMRC Project Grants

Funding Amount: $454,500.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Oncology and Carcinogenesis

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cell migration | epithelial biology | invasion and metastases | membrane protein | metastasis | squamous carcinoma | tetraspanin | wound healing