A Randomised Controlled Trial of CPAP versus Oral Appliance in Obstructive Sleep Apnoea

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/457557

Funding Status
Closed

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Funded Activity Summary

Obstructive sleep apnoea (OSA) is a very common disorder, affecting approximately 25% of women and 9% of men in the middle-aged workforce . It is characterised by repetitive, complete or partial closure of the throat passage during sleep, resulting in sleep disturbance and low oxygen levels. When associated with symptoms, termed Obstructive Sleep Apnoea Syndrome, it occurs in 4% of men and 2% of women in middle age. OSA is recognised as a serious public health problem. Continuous Positive Airway Pressure is the gold standard treatment, and has been demonstrated to produce major health benefits. However, there is growing evidence supporting the use of oral appliances to treat OSA, which are potentially simpler to use. It is thought that these work by enlarging the throat passage. Recent practice guidelines recommend their use as a first line treatment for mild to moderate OSA. The aim of this project is to directly compare the health benefits achievable with these therapies, taking into account patient compliance and preference, and will assist in the development of protocols for the use of these treatments in clinical practice.

Funded Activity Details

Start Date: 01-01-2007

End Date: 01-01-2009

Funding Scheme: NHMRC Project Grants

Funding Amount: $416,155.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Respiratory Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Blood pressure | Continuous Positive Airway Pressure | Dental Treatments | Dental treatments | Obstructive sleep apnoea | Randomised controlled trial | Sleepiness

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