Characterization of a novel secretion system necessary for Porphyromonas gingivalis virulence.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/509326

Funding Status
Closed

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Funded Activity Summary

In this study we will characterize a novel bacterial secretion system that we have discovered. This sytem mediates the secretion of proteins from the bacterial cell and their attachment to the cell surface. This system is essential for the virulence of Porphyromonas gingivalis, a bacterium associated with chronic periodontitis. The chacterization of this system may offer opportunities for the development of new treatments to target this disease.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $596,412.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical physiology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Bacterial secretion system | Chronic inflammation | Oral health | Oral microbiology | Periodontal disease | Porphyromonas gingivalis | Proteinase | Virulence traits

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