The immunoregulatory domains and binding interactions of human respiratory syncytial virus non-structural proteins

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/511020

Funding Status
Closed

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Funded Activity Summary

Human respiratory syncytial virus (HRSV) is the leading cause of lower respiratory tract disease in infants and yet there are no vaccines available. HRSV exacerbates disease by interfering with the innate immune response. We aim to establish the mechanism by which this occurs by identifying the cellular-viral protein interactions involved, and by identifying the specific regions of the viral proteins responsible. This information will allow targeted vaccines and antivirals to be developed.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $484,051.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Applied immunology (incl. antibody engineering xenotransplantation and t-cell therapies)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

antiviral | antiviral therapy | immunocompromised patients | microbiology-virology | molecular biology | protein-protein interactions | proteomics | respiratory diseases in children | respiratory syncytial virus | viral bronchiolitis

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