Regulation of caspase-1 activation and inflammation by PYD and CARD proteins

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/511227

Funding Status
Closed

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Funded Activity Summary

Inflammatory diseases such as rheumatoid arthritis are among the largest contributors to health expenditure in Australia, and the impact of these diseases will increase dramatically over the next 15-20 years as the population ages. This research will reveal new insights into the regulation of caspase-1 activation and secretion of interleukin-1b, the primary cause of chronic and acute inflammation, and will enhance future approaches for development of treatments for inflammatory disease.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $364,549.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry And Cell Biology Not Elsewhere Classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

NMR spectroscopy | biochemistry | familial Mediterranean fever | infection-acute inflammation | inflammatory diseases | innate immunity | protein structure | protein-protein interaction | rheumatoid arthritis

Related Links

ACN 633 798 857