Integrin intracellular transport, expression and function in macrophages regulates inflammation during wound healing

Funding Activity

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Funded Activity Summary

Burns are one of the most common and devastating forms of trauma; 70% occur in young children. Burns scars may be aesthetically disfiguring and functionally disabling, as well as psychosocially damaging. The study will identify how macrophages enter, function and persist in a burn wound to regulate inflammation, which if prolonged results in delayed healing and excess scar formation, and will generate multiple targets for potential future wound healing therapies.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $434,134.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Interactions (Incl. Adhesion, Matrix, Cell Wall)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Inflammation | burns patients | cell adhesion | cell migration | inflammation | integrins | membrane transport | scar formation | wound healing