Function of the Vitamin D Receptor in Hepatic Non-Parenchymal Cells

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/512354

Funding Status
Closed

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Funded Activity Summary

Nuclear receptors are sensors that control many aspects of metabolism, including responses to injury. Our work and has suggested that the Vitamin D Receptor (VDR) may play a vital role in how the liver responds to damage and whether the liver will the scar and move on to cirrhosis. Our experiments will determine if this is so, and in which cells VDR has this role. This work will provide a basis for future treatments to improve or prevent severe liver diseases.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $509,304.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

Amelioration of liver diseases | Chronic liver diseases | Development of novel therapies | Hepatic gene regulation | Hepatic non-parenchymal cells | Liver injury and inflammation | Nuclear bile acid receptors | Pathogenesis of liver diseases | Prevention of cirrhosis

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