Mechanisms of autoantibody mediated axonal injury in inflammatory demyelinating neuropathies

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/512537

Funding Status
Closed

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Funded Activity Summary

Destruction of nerve fibres (axons) accompanies demyelination and may be responsible for most of the deficit in multiple sclerosis and immune neuropathies. This project will investigate the role of recently described antibodies against a normal component of the axon in axonal damage in both animal models and in patients with immune neuropathies. The project could have a major effect on approaches to management of these diseases.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $580,197.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical mycology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

autoantibodies | autoimmune disease | autoimmune diseases | axonal excitability | axonal injury | inflammatory brain disease | inflammatory nerve disease | multiple sclerosis | nerve injury | neuroimmunology

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