Role of the Ets family transcription factor Erg in stem cell function and hematopoiesis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/516726

Funding Status
Closed

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Funded Activity Summary

The cells responsible for producing blood are called hematopoietic stem cells (HSCs). Our research is focused on the genes that control HSC growth and development. We have discovered that a gene known to cause cancer, Erg, plays a critical role in regulating this process. This Project will tease apart the mechanism by which it does so, provide insights into how Erg can trigger cancer, and help us understand the molecular network of regulators that control blood cell production.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $413,775.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry And Cell Biology Not Elsewhere Classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

disease models, animal | haematological abnormalities | haematopoiesis | haematopoietic stem cells | leukaemia | molecular genetics | murine models | stem cells | transcription factor

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