Targeting critical nodes on the IGF1-PI3K pathway to improve function of the failing heart

Funding Activity

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Funded Activity Summary

Heart failure is a major clinical problem which is becoming worse as our population grows older and comorbidities such as obesity and diabetes become more prevalent. Current heart failure therapeutics largely delay disease progression. This research proposal focuses on strategies designed to improve function of the failing heart, as opposed to simply delaying disease progression. This approach will lead to the development of new therapeutics.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $512,947.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nutrigenomics and personalised nutrition

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Cardiac hypertrophy | Cardiovascular disease | Heart failure | Molecular mechanisms | Mouse genetics | Targeted gene delivery

ACN 633 798 857