Defining mechanisms of follistatin-mediated muscle adaptation, for treatment of frailty and muscle-related diseases

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/526648

Funding Status
Closed

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Funded Activity Summary

Physical frailty-weakness is one of the most common symptoms of serious illness and a key cause of death. I propose to study a new model of skeletal muscle growth, to learn more about the causes of wasting in muscle-related diseases. The work will identify cell mechanisms that cause loss of muscle strength, and will help develop novel treatment approaches to prevent or reverse physical frailty in illness. New therapies to combat frailty are vital to improve the health of our community.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $557,478.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry And Cell Biology Not Elsewhere Classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

aging-asociated muscle wasting | cancer-related cachexia | cell signalling and signal transduction | frailty and weakness | gene expression | gene therapy | muscle atrophy | neuromuscular disease | recombinant viral vectors | skeletal muscle growth and wasting

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