Roles of integrin receptors and the Helicobacter pylori protein CagL in gastritis and gastric cancer

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/545983

Funding Status
Closed

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Funded Activity Summary

How the bacterium Helicobacter pylori (Hp) causes gastritis and gastric cancer in the stomach is not well understood. Here we investigate the molecular languages used by Hp to deregulate the normal functions of the human stomach cells. The research outcomes will on one hand help us to better understand how Hp causes diseases, and on the other hand, facilitate the development of new antibiotics or treatment therapies to combat gastric cancers and gastritis.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $290,697.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry And Cell Biology Not Elsewhere Classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Acute gastritis and peptic ulcer | Chronic gastritis | Chronic inflammation caused by bacterial infections | Gastric adenocarcinoma | Molecular basis of Helicobacter-induced carcinogenesis | Mucosa-associated lymphoid tissue (MALT) lymphoma | Roles of integrins and their signalling in gastric diseases | Strcuture-function of bacterial virulence factors | The molecular basis of Helicobacter-host cell interactions | The molecular pathogenesis of Heliocbacter infections

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