Human cytomegalovirus gene expression and functions during latent infection and reactivation

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/570962

Funding Status
Closed

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Funded Activity Summary

Human cytomegalovirus has the ability to hide in the body in a latent form for the life of the host. However, the virus can awaken (reactivate) from its latent state, producing new infectious virus and disease. It is in immunosuppressed people such as transplant patients that reactivation from latency causes significant morbitity and mortality, yet the latent infection remains very poorly understood. This project will identify and define the functions of viral genes that facilitate latency.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $789,473.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Applied immunology (incl. antibody engineering xenotransplantation and t-cell therapies)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Allogeneic transplantation | Anti-latency drugs | Cytomegalovirus induced graft versus host disease | Human cytomegalovirus | Human cytomegalovirus pneumonia | Latent infection | Myeloid progenitor cells | Viral gene expression and function during latency

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