Cutaneous inflammation, bone marrow dendritic cells, and implications for immune responses and immune homeostasis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/572660

Funding Status
Closed

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Funded Activity Summary

With inflammation of the skin due to excessive sun exposure or chemicals, biological signals are sent to the bone marrow where immune fighting cells are generated. However, the immune system must not overreact. We have measured bone marrow derived immune cells with reduced function following skin inflammation which we propose is part of homeostasis. We need to better understand how these cells are altered and for how long they are altered.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $327,151.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical chemistry (incl. diagnostics)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Bone marrow | Dendritic cells | Immune responses | Immunomodulation | Inflammation | Ultraviolet radiation | mice | skin cancer

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