microRNA dysregulation as a mechanism underlying muscle wasting

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/586649

Funding Status
Closed

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Funded Activity Summary

Frailty caused by muscle wasting shortens many peoples' lives and costs hundreds of billions of dollars in care and lost productivity annually. In the hope of finding ways to treat frailty, we will study whether naturally-occurring microRNA molecules are responsible for disrupting gene expression to cause muscle disease. We will identify which types of microRNA are altered in muscle diseases, and test whether adjusting microRNA levels with new approaches can prevent-treat muscle wasting.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $514,454.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Molecular Medicine

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cachexia | chronic illness | gene expression - regulation | gene therapy - molecular medicine | intensive care | microRNA - RNA-interference | muscle wasting | muscular dystophy - myopathy | neuromuscular disease | sarcopenia

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