Transcription at the centromere: roles in formation, maintenance and function

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/607317

Funding Status
Closed

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Funded Activity Summary

Every human has 46 chromosomes. Chromosomes are structures that carry genes in all our cells. The centromere is an essential component of a chromosome which governs the process of cell division and separation of replicated chromosomes. Defects in centromere function cause abnormalities in cell division that in turn cause a variety of genetic diseases including cancer. We propose to investigate the role that transcription at the centromere plays in determining correct centromere function.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $549,092.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Genome Structure and Regulation

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cancer | cancer biology | cell cycle regulation | cell division | chromatin | chromatin structure | chromosomal abnormality | epigenetics | genetic disease | molecular basis of disease

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