The implications of focal adhesion organization on signal transduction

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/630545

Funding Status
Closed

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Funded Activity Summary

The areas of a cell's attachment to their surroundings are known as focal adhesion. Apart from linking the inside and outside of a cell, focal adhesions act as a communication centre transmitting incoming and outgoing signals. How focal adhesions themselves are organized is currently not known. We propose to adhere cells to model surfaces to control the protein and membrane structure of focal adhesions and measure how focal adhesion structure affects cell communication.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $565,614.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Receptors and Membrane Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Adhesion | Cell adhesion | Cell signalling | Endothelial cells | Membrane structure | Model surfaces | Molecular basis of disease | Signal transduction

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