Rad50 protects the integrity of the genome to minimise disease risk

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/631425

Funding Status
Closed

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Funded Activity Summary

Exposure to both endogenous products of metabolism as well as a variety of exogenous agents (UV, X-rays) increases the risk of cancer and other diseases. This project is designed to further investigate a novel defect in the Rad50 gene that predisposes to genetic instability and cancer. In short we have described for the first time a patient with a defect in the Rad50 gene. This information will assist in understanding our defence systems against oxidative stress to reduce the risk of disease.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $524,222.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Cell Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Ataxia | Cancer | DNA Damage | Genetic Disease | Genetic Disorders | Neurodegeneration | Signal Transduction

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