A single-stranded DNA binding protein implicated in the cellular response to DNA damage.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/632610

Funding Status
Closed

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Funded Activity Summary

Humans have evolved multiple mechanisms to ensure the integrity of their genetic information, which is carried by DNA. Each cell suffers more than 100 000 insults a day to its DNA; therefore an effective DNA damage response is crucial for the maintenance of genetic integrity and for survival. This research proposal aims to explore the molecular actions of hSSB2, a newly discovered player in the cell's arsenal for repairing harmful DNA damage.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $503,816.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Characterisation of Biological Macromolecules

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

DNA damage | DNA repair | cancer | genetic predisposition to disease | molecular mechanisms | protein structure | protein-protein interaction | ultraviolet radiation exposure

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